For an oocyte for being Completely ready for fertilization and expansion into an embryo, the best list of genes must be turned on. Namekawa suspected that this pre-programming of your oocyte genome happens in numerous stages — the 1st one starting off across the time a feminine is born. He believed that chromatin remodeling proteins did Considerably of the do the job, by shifting spools close to.
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This protein may perhaps “set up and keep the chromatin point out,” says Namekawa — trying to keep the spools set up and also the oocytes genetically primed as being the mouse matures.
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